quoll

Library · a11aca61-2081-49ed-a8a2-ae5439b50a95

Ortin et al 2021

file

file:///home/pi/welfare_docs/Animals Assured/Research/Trisolfen/Ortin et al 2021.pdf

JSON JSON-LD CSV

No contextual analysis available. Re-ingest with quoll add -f <path> to generate claim analysis, evidence mapping, and other enrichments.

Full text
Management and animal welfare Poster presentation s Genetic Resources (2021) S1 International Congress on Sheep and Goats 68 Abstract book Effect of a topical wound anaesthesia formulation on the cortisol and the acute phase responses of lambs undergoing tail docking. Ort ín, A. 1 , Borobia, M. 1 Ramos, J.J. 1 , Lacasta, D. 1 , Ferrer, L.M. 1 , Tejedor, M.T. 2 , Ruiz, H. 1 , Jimenez, C. 3 , 4 and W indsor, P.A. 1 1 Animal Pathology Department , Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA ) , Veterinary Faculty of Zaragoza , Zar agoza , Spain 2 Anatomy, Embryology and Animal Genetics Department , CIBER CV (Universidad de Zaragoza - IIS ) , (Universidad de Zaragoza - CITA ) , Veterinary Faculty of Zaragoza , Zaragoza , Spain 3 Gabinete T écnico Veterinario S.L. C/ Isla conejera s/n. 50013 Zaragoza, Spain 4 Sydney School of Veterinary Science, The University of Sydney , Sydney , Australia Contact: Aurora Ortín , aortin@unizar.es Abstract: In this study we evaluated the effect of a topical wound gel formu lation containing local anaesthetics lignocaine and bupivacaine, with cetrimide and adrenalin (Tri - Solfen®; TS) on the concentrations of serum cortisol (SC) and the acute phase protein serum amyloid A (SAA) in tail - docked lambs. Forty - four female lambs wit h similar weights were recruited into four equal cohorts: Groups A and C, the tail was excised with a scalpel without anaesthesia and Groups B and D, the tail was surgically excised and stitched under general anaesthesia (GA). C and D groups were immediate ly sprayed with TS. Blood samples were collected before tail docking and at different time intervals post - tail excision. Concentra - tions of SC and SAA were determined using ELISA assays (Salivary Cortisol ELISA SLV - 2930, DRG Diagnostics, Marburg, Germany; PHASE TM Serum Amyloid A Assay, Tridelta Development Ltd., Maynooth, Ireland). Statistical analysis was preformed using IBM SPSS statistics version 26 (2019) software (IBM, Armonk, NY, USA). SC concentration did not change significantly over time in cohort s tail - docked under GA (B & D), but peaked at 30 min post tail removing without anaesthesia (A & C), and treatment with TS (C) appeared to reduce this cortisol response. In cohorts B & D , SAA concentrations increased significantly 48 hours after tail dock ing, as it is expected after a noxious stimulus, but treatment with TS avoided the elevation of SAA at this time point in lambs where the tail was excised without anaesthesia. These results appear to indicate that treatment with TS reduces cortisol and SAA responses in lambs tail docked without anaesthesia, although further research is needed to corroborate these findings. References: Marini, D., Colditz, I.G., Hinch, G., Petherick, J.C., Lee, C., 2017. Self - administration by consumption of flunixin in fee d alleviates the pain and inflammation associated with castration and tail docking of lambs. Appl. Anim. Behav. Sci. 188, 26 – 33. DOI: 10.1016/j.applanim.2016.12.008. Paull, D.R., Lee, C., Colditz, I.G., Atkinson, S.J., Fisher, A.D., 2009. The effect of a t opical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing. Aust. Ve t. J. 85, 98 – 106. DOI: 10.1111 /j.1 751 - 0813.2009.00429.x. Tothova C, Nagy O, Kovac G. 20 14. Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review. Vet. Med. 59, 163 - 168. DOI: 10.17221/7478 - VETMED.
Text excerpts (3 chunks)

chunk 0 · 448 tokens

Management and animal welfare Poster presentation s Genetic Resources (2021) S1 International Congress on Sheep and Goats 68 Abstract book Effect of a topical wound anaesthesia formulation on the cortisol and the acute phase responses of lambs undergoing tail docking. Ort ín, A. 1 , Borobia, M. 1 Ramos, J.J. 1 , Lacasta, D. 1 , Ferrer, L.M. 1 , Tejedor, M.T. 2 , Ruiz, H. 1 , Jimenez, C. 3 , 4 and W indsor, P.A. 1 1 Animal Pathology Department , Instituto Agroalimentario de Aragón - IA2 (Universidad de Zaragoza - CITA ) , Veterinary Faculty of Zaragoza , Zar agoza , Spain 2 Anatomy, Embryology and Animal Genetics Department , CIBER CV (Universidad de Zaragoza - IIS ) , (Universidad de Zaragoza - CITA ) , Veterinary Faculty of Zaragoza , Zaragoza , Spain 3 Gabinete T écnico Veterinario S.L. C/ Isla conejera s/n. 50013 Zaragoza, Spain 4 Sydney School of Veterinary Science, The University of Sydney , Sydney , Australia Contact: Aurora Ortín , aortin@unizar.es Abstract: In this study we evaluated the effect of a topical wound gel formu lation containing local anaesthetics lignocaine and bupivacaine, with cetrimide and adrenalin (Tri - Solfen®; TS) on the concentrations of serum cortisol (SC) and the acute phase protein serum amyloid A (SAA) in tail - docked lambs. Forty - four female lambs wit h similar weights were recruited into four equal cohorts: Groups A and C, the tail was excised with a scalpel without anaesthesia and Groups B and D, the tail was surgically excised and stitched under general anaesthesia (GA). C and D groups were immediate ly sprayed with TS. Blood samples were collected before tail docking and at different time intervals post - tail excision. Concentra - tions of SC and SAA were determined using ELISA assays (Salivary Cortisol ELISA SLV - 2930,

chunk 1 · 448 tokens

different time intervals post - tail excision. Concentra - tions of SC and SAA were determined using ELISA assays (Salivary Cortisol ELISA SLV - 2930, DRG Diagnostics, Marburg, Germany; PHASE TM Serum Amyloid A Assay, Tridelta Development Ltd., Maynooth, Ireland). Statistical analysis was preformed using IBM SPSS statistics version 26 (2019) software (IBM, Armonk, NY, USA). SC concentration did not change significantly over time in cohort s tail - docked under GA (B & D), but peaked at 30 min post tail removing without anaesthesia (A & C), and treatment with TS (C) appeared to reduce this cortisol response. In cohorts B & D , SAA concentrations increased significantly 48 hours after tail dock ing, as it is expected after a noxious stimulus, but treatment with TS avoided the elevation of SAA at this time point in lambs where the tail was excised without anaesthesia. These results appear to indicate that treatment with TS reduces cortisol and SAA responses in lambs tail docked without anaesthesia, although further research is needed to corroborate these findings. References: Marini, D., Colditz, I.G., Hinch, G., Petherick, J.C., Lee, C., 2017. Self - administration by consumption of flunixin in fee d alleviates the pain and inflammation associated with castration and tail docking of lambs. Appl. Anim. Behav. Sci. 188, 26 – 33. DOI: 10.1016/j.applanim.2016.12.008. Paull, D.R., Lee, C., Colditz, I.G., Atkinson, S.J., Fisher, A.D., 2009. The effect of a t opical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing. Aust. Ve t. J. 85, 98 – 106. DOI: 10.1111 /j.1 751 - 0813.2009.00429.x. Tothova C, Nagy O, Kovac G. 20 14. Acute phase proteins and their use in the diagnosis of

chunk 2 · 59 tokens

J. 85, 98 – 106. DOI: 10.1111 /j.1 751 - 0813.2009.00429.x. Tothova C, Nagy O, Kovac G. 20 14. Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review. Vet. Med. 59, 163 - 168. DOI: 10.17221/7478 - VETMED.