CSIRO FD McMaster Laboratory

…PAULL, C LEE, IG COLDITZ, S$] ATKINSON and AD FISHER CSIRO Livestock Industries, FD McMaster Laboratory, Armidale NSW 2350 Andrew. Fisher@csiro,au } { ulesing is a surgical procedure in which two strips…

…One block per day was subjected to The experiment was undertaken at CSIRO’s FD experimentation over a 2-week period. The day before castration McMaster and Laboratory, Armidale, NSW and was…

CSIRO PUBLISHING Animal Production Science http://dx.doi.org/10.1071/AN14012 Evaluating the efficacy of a topical anaesthetic formulation and ketoprofen, alone and in combination, on the pain sensitivity of dehorning…

…In total, prolonged clinical course and debilitating impacts of FD on grazing 7/36 (19.4%) cattle had not returned to mobility by day 9, indicating animals. Although a subjective measurement, these…

…Commonwealth Scientific and Industrial Research Organi- sation (CSIRO); 2015 [updated 27 February 2015; cited 2016 10 February]. Available: http://www.csiro. au/en/Research/AF/Areas/Animal-Science/Premium-livestock-breeds/Hornless…

mulesing such as; rear leg collapse, dog sitting, lateral lying or lying with cradle for 4-hour wound sensitivity assessment, before being head flat, prominent tremors and shaking, inability to stand and/ returned to their dams and turned out to pasture. Lambs were or marked and unusual leaning. re-yarded 2 and 4 weeks later when wounds were examined and re-photographed. Wound healing Wound healing was assessed by mapping wound surface area Trial 2 This trial examined wound sensitivity to P stimulation (WSA) using digital photography and Scion Image PC® digital and pain-related behaviour in 80 lambs undergoing both image analysis software (National Institute Health, USA). Digital mulesing and marking. The first 24 lambs were allocated to photographs were taken with a linear scale held against the wool wound sensitivity testing. General management with mulesing immediately above the wound. Using the image analysis was as above. Alternate lambs were treated with Tri-Solfen® or software, pixels per cm2 were calculated, then the wound outline remained untreated. Spinosyn (Extinosad®, Elanco Animal was mapped and surface area was calculated in cm2. Two Health, Macquarie Park, NSW) with blue food dye added to recordings were made for each image by two separate assessors achieve blinding was applied according to recommendations as a and the results were averaged to provide the final surface area flystrike preventative treatment. Lambs remained in the cradle measurement. Wounds were photographed at the time of for 3 min after which skin and wound sensitivity was performed. mulesing (before application of any treatment) and 14 and 28 They were then housed in a mixed treatment group in an indoor days later. Images were identified by lamb tag number and pen and returned to the

Posted on Authorea 16 Sep 2020 — The copyright holder is the author/funder. All rights reserved. No reuse without permission. — https://doi.org/10.22541/au.160029789.93744641 — This a preprint and has not been peer reviewed. Data may be preliminary. Efficacy and application of a novel topical anaesthetic wound formulation for treating cattle with Foot-and-Mouth disease: a field trial in Cameroon Sevidzem Lenze1 , Jacques Mavoungou1 , Kong Burinyuy1 , Koumba Armel1 , Simon Dickmu1 , James Young2 , Peter Thomson3 , and Peter Windsor2 1 Affiliation not available 2 University of Sydney 3 School of Life and Environmental Sciences September 16, 2020 Abstract Recently, a wound dressing formulation, (Tri-Solfen®, Medical Ethics Pty Ltd, Australia; TS) registered for use in ruminant husbandry in Australia, was registered for Foot-and-Mouth Disease (FMD) therapy in large ruminants in Laos, following clinical observations of improved welfare and healing following treatment of FMD lesions. In November 2019, an FMD outbreak in Cameroon provided an opportunity for a field trial, comparing clinical responses and recoveries to treatments on a sample of cattle (n = 36) comprising three equal groups of animals (n = 12), comparing responses to three treatments:(i) the application to lesions of TS, (ii) the administration of parenteral oxytetraycline commonly used for FMD in Cameroon; and (iii) an untreated control group (C). Appetite scores, lesion healing scores, and changes in dimensions of lesions, were recorded over a 15-day study period. Cattle treated with TS achieved both superior appetite and lesion healing scores with more rapid reduction in dimensions of lesions than other groups. Farmer observations indicated the TS treatment group had a more rapid return to eating with

Analgesia for Surgical Husbandry Procedures in Sheep and Other Livestock Dr Meredith L Sheil, Animal Ethics Pty Ltd, Associate Sydney University Faculty of Veterinary Science SUMMARY Surgical husbandry procedures in livestock are invariably associated with pain and stress, yet are traditionally performed without analgesia. Concern for the welfare of animals undergoing these procedures is contributing to major conflicts between farmers and animal advocacy organisations with important negative trade implications. Whilst the ultimate long term solution is to breed animals that do not require these procedures, or to find painless alternative practices, this will take time and a significant research effort in most cases. In the meantime, there is an urgent need to find a more immediate way to alleviate welfare concerns. This can be achieved by developing effective low-cost analgesia for on-farm use, to allow surgical procedures in livestock to be performed as humanely as surgical procedures in domestic animals and humans, while long term solutions are pursued and implemented. The first step in reaching this goal was realised with the development and commercialisation of Tri-Solfen® (Bayer Animal Health, Gordon NSW). Tri-Solfen® is a low-cost, farmer-applied topical anaesthetic, haemostatic and antiseptic wound care product that significantly alleviates pain associated with mulesing. Subsequent research identified that pre-operative administration of Carprofen enhanced the analgesic effects. Used together these agents eliminate pain-related behaviour for 24 hours post mulesing and abolish the cortisol response, thus providing highly effective analgesia that equates to (if not surpasses) that which is achieved for routine surgical procedures in veterinary clinics, such as

m (Goods and Services Tax) Act 1999 and related legislation passed by the Federal Government; "Indication" means a specific animal welfare use-case or application of the Product for which an assessment is to be performed under Schedule 2; "Insolvency Administration" means any form of external administration of the property of any person whether under the provisions of the Corporations Law, the Bankruptcy Act 1966 or any other similar legislation or otherwise including bankruptcy, winding up, liquidation, voluntary administration and the appointment of a receiver or a receiver and manager; "Intellectual Property" means all forms of intellectual property rights throughout the world including copyright, registered patent, design, trademark and confidential information including know-how and trade secrets; "Manager" means the person described in Item 5 of Schedule 1; "Moral Rights" has the meaning given to it in the Copyright Amendment (Moral Rights) Act 2000 (Cth); "Product" means Tri-Solfen, a topical anaesthetic and antiseptic wound management product manufactured by the Client; "related company" has the meaning given to a related body corporate under the Corporations Act; "rights and claims" includes all rights, entitlements, claims, debts, actions, demands, suits, proceedings, liabilities, losses, sums of money, damages, expenses and costs; "Services" includes the services described in Schedule 2 and any additional or ancillary services agreed between the Company and the Client in writing from time to time; "Term" means the period from the Commencement Date until the Termination Date unless this Deed is extended by mutual agreement by the parties in writing or this Deed is otherwise terminated; and "Termination Date" means the date set out in Item 4 of Schedule 1. 1.2

…Acute cortisol responses of calves to four methods of dustries Standing Committee, CSIRO Publications, Collingwood, dehorning by amputation. Aust. Vet. J. 76:123–126. Victoria, Australia. Sylvester, S. P., K. J. Stafford…