Contagious Ecthyma

Communication The Treatment of Contagious Ecthyma in Lambs with a Local Anaesthetic/Antiseptic Wound Formulation Lowers Serum Amyloid A Responses Aurora Ortín 1,2, * , Sergio Villanueva-Saz 1,2 , Delia Lacasta 1…

anish Policy for Animal Protection RD53/2013, meeting countries, and where available, existing live-attenuated or the European Union Directive 2010/63 on the protection of scab-based vaccines may revert to virulence and are not animals used for experimental and other scientific fully protective. This could be due to genetic deletions purposes. present in attenuated vaccines, that may significantly reduce their immunogenicity and efficacy, and genetic Animals heterogeneity of field strains.7–9 One-month-old lambs (n=14) with similar weights and The treatment of this disorder involves standard naturally infected with orf were recruited from a farm hygiene practices and in numerous cases, management of where a natural outbreak of orf disease was occurring. presumptive secondary infections, usually with antibiotic The 1800 Lacaune sheep farm was located in a small treatments.2 As reducing antibiotic use in livestock has village of the Pyrenees mountains. Due to high prolificacy become a priority for the management of antimicrobial (2.2), some lambs were routinely artificially fed milk by an resistance (AMR) risk, there is a need for treatment pro­ artificial lactation machine. These lambs were kept in tocols that provide more effective topical treatment of orf a separate pen with proper cleaning and disinfection con­ cases. Recent studies have confirmed the efficacy of the ditions, although the farmers reported the lambs frequently wound therapy formulation Tri-Solfen® (TS) (Animal had recurrent orf infections. The lambs selected for the Ethics Pty Ltd, Australia) for reducing pain and hastening experiment were in the early stages of orf infection when healing of skin and mucosal lesions in sheep and cattle. lesions were initially diagnosed. The lambs were co- The