…dos Santos, É.R.; Bridi, A.M.; da Silva, C.A.; Alfieri, A.A.; Fritzen, J.T.T.; Terto, D.K.; Correia, E.R. Gender Effects on Pork Quality and Calpain-1…
T. Bas Rodenburg
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…Effects of the EDITED BY T. Bas Rodenburg, Utrecht University, Netherlands REVIEWED BY Regula Bettschart, injection method and interval University of Zurich, Switzerland Nancy De Briyne, Federation of Veterinarians of between injection…
…Different results were reported by Ba et al. (2019) [32], who observed a decreased water-holding capacity in meat with an increasing slaughter weight of pigs. The present study showed statistically significant…
…Effects of the EDITED BY T. Bas Rodenburg, Utrecht University, Netherlands REVIEWED BY Regula Bettschart, injection method and interval University of Zurich, Switzerland Nancy De Briyne, Federation of Veterinarians of between injection…
eting interests The authors declare no competing interests. Additional information Supplementary Information The online version contains supplementary material available at https://doi .org/1 0.10 38/s41598- 025-91551-6. Correspondence and requests for materials should be addressed to P.H.E.T. Reprints and permissions information is available at www.nature.com/reprints. Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:/ /creativec ommo ns.org /licenses/
eting interests The authors declare no competing interests. Additional information Supplementary Information The online version contains supplementary material available at https://doi .org/1 0.10 38/s41598- 025-91551-6. Correspondence and requests for materials should be addressed to P.H.E.T. Reprints and permissions information is available at www.nature.com/reprints. Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:/ /creativec ommo ns.org /licenses/
gh degree of variability in the literature of test methods employed and outcomes obtained, there is nevertheless a growing body of evidence to suggest that some piglet responses to pain induced by castration, are more consistently reproduced and specific to the pain experienced during castration than others. In this narrative review, we examine the potential indicators of pain in neonatal piglets undergoing castration to determine the optimal methods currently available to most accurately detect pain and assess pain mitigation. Abstract: Analgesic products for piglet castration are critically needed. This requires extensive animal experimentation such as to meet regulatory-required proof of efficacy. At present, there are no validated methods of assessing pain in neonatal piglets. This poses challenges for investigators to optimize trial design and to meet ethical obligations to minimize the number of animals needed. Pain in neonatal piglets may be subtle, transient, and/or variably expressed and, in the absence of validated methods, investigators must rely on using a range of biochemical, physiological and behavioural variables, many of which appear to have very low (or unknown) sensitivity or specificity for documenting pain, or pain-relieving effects. A previous systematic review of this subject was hampered by the high degree of variability in the literature base both in terms of methods used to assess pain and pain mitigation, as well as in outcomes reported. In this setting we provide a narrative review to assist in determining the optimal methods currently available to detect piglet pain during castration and methods to mitigate castration-induced pain. In overview, the optimal outcome variables identified are nociceptive motor and vocal response scores during
animals Article Exploratory Survey on European Consumer and Stakeholder Attitudes towards Alternatives for Surgical Castration of Piglets Marijke Aluwé 1, *, Evert Heyrman 1 , João M. Almeida 2 , Jakub Babol 3 , Gianni Battacone 4 , Jaroslav Čítek 5 , Maria Font i Furnols 6 , Andriy Getya 7 , Danijel Karolyi 8 , Eliza Kostyra 9 , Kevin Kress 10 , Goran Kušec 11 , Daniel Mörlein 12 , Anastasia Semenova 13 , Martin Škrlep 14 , Todor Stoyanchev 15 , Igor Tomašević 16 , Liliana Tudoreanu 17 , Maren Van Son 18 , Sylwia Żakowska-Biemans 9 , Galia Zamaratskaia 19 , Alice Van den Broeke 1 and Macarena Egea 20 1 Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Animal Sciences Unit, 9090 Melle, Belgium; evert.heyrman@ilvo.vlaanderen.be (E.H.); alice.vandenbroeke@ilvo.vlaanderen.be (A.V.d.B.) 2 Instituto Nacional de Investigação Agrária e Veterinária (INIAV), Quinta da Fonte Boa, 2005-048 Vale de Santarém, Portugal; joaoalmeida@iniav.pt 3 Department of Biomedical Science and Veterinary Public Health, Swedish University of Agricultural Sciences, Box 7015, 750 07 Uppsala, Sweden; jakub.babol@slu.se 4 Department of Agriculture, University of Sassari, Viale Italia 39, 07100 Sassari, Italy; battacon@uniss.it 5 Department of Animal Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague (CZU), Kamycka 129, 16500 Prague, Czech Republic; citek@af.czu.cz 6 Institute for Food and Agriculture Research and Technology (IRTA), Product Quality Program, Finca Camps i Armet, 17121 Monells, Girona, Spain; maria.font@irta.cat 7 Animal Breeding Department, National University of Life and Environmental Sciences of Ukraine (NULES), Henerala Rodimtseva 19, 03041 Kyiv, Ukraine; getya@ukr.net 8 Department of Animal
animals Article Exploratory Survey on European Consumer and Stakeholder Attitudes towards Alternatives for Surgical Castration of Piglets Marijke Aluwé 1, *, Evert Heyrman 1 , João M. Almeida 2 , Jakub Babol 3 , Gianni Battacone 4 , Jaroslav Čítek 5 , Maria Font i Furnols 6 , Andriy Getya 7 , Danijel Karolyi 8 , Eliza Kostyra 9 , Kevin Kress 10 , Goran Kušec 11 , Daniel Mörlein 12 , Anastasia Semenova 13 , Martin Škrlep 14 , Todor Stoyanchev 15 , Igor Tomašević 16 , Liliana Tudoreanu 17 , Maren Van Son 18 , Sylwia Żakowska-Biemans 9 , Galia Zamaratskaia 19 , Alice Van den Broeke 1 and Macarena Egea 20 1 Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Animal Sciences Unit, 9090 Melle, Belgium; evert.heyrman@ilvo.vlaanderen.be (E.H.); alice.vandenbroeke@ilvo.vlaanderen.be (A.V.d.B.) 2 Instituto Nacional de Investigação Agrária e Veterinária (INIAV), Quinta da Fonte Boa, 2005-048 Vale de Santarém, Portugal; joaoalmeida@iniav.pt 3 Department of Biomedical Science and Veterinary Public Health, Swedish University of Agricultural Sciences, Box 7015, 750 07 Uppsala, Sweden; jakub.babol@slu.se 4 Department of Agriculture, University of Sassari, Viale Italia 39, 07100 Sassari, Italy; battacon@uniss.it 5 Department of Animal Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague (CZU), Kamycka 129, 16500 Prague, Czech Republic; citek@af.czu.cz 6 Institute for Food and Agriculture Research and Technology (IRTA), Product Quality Program, Finca Camps i Armet, 17121 Monells, Girona, Spain; maria.font@irta.cat 7 Animal Breeding Department, National University of Life and Environmental Sciences of Ukraine (NULES), Henerala Rodimtseva 19, 03041 Kyiv, Ukraine; getya@ukr.net 8 Department of Animal
he potential of misinterpreting trial outcomes. Although there is a high degree of variability in the literature of test methods employed and outcomes obtained, there is nevertheless a growing body of evidence to suggest that some piglet responses to pain induced by castration, are more consistently reproduced and specific to the pain experienced during castration than others. In this narrative review, we examine the potential indicators of pain in neonatal piglets undergoing castration to determine the optimal methods, currently available to most accurately detect pain, and assess pain mitigation. Abstract: Analgesic products for piglet castration are critically needed. This requires extensive animal experimentation such as to meet regulatory-required proof of efficacy. At present, there are no validated methods of assessing pain in neonatal piglets. This poses challenges for investigators to optimize trial design and to meet ethical obligations to minimize the number of animals needed. Pain in neonatal piglets may be subtle, transient and / or variably expressed and, in the absence of validated methods, investigators must rely on using a range of biochemical, physiological and behavioural variables, many of which appear to have very low (or unknown) sensitivity or specificity for documenting pain, or pain-relieving effects. A previous systematic review of this subject was hampered by the high degree of variability in the literature base both in terms of methods used to assess pain and pain mitigation, as well as in outcomes reported. In this setting we provide a narrative review, to assist in determining the optimal methods currently available to detect piglet pain during castration and methods to mitigate castration-induced pain. In overview, the optimal outcome