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The University of Sydney

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Efficacy and application of a novel topical anaesthetic wound formulation for treating cattle with Foot-and-Mouth disease: A field trial in Cameroon 95%
Sevidzem S. Lendzele; Jacques F. Mavoungou; Kong A. Burinyuy; Koumba A. Armel; Simon J. Dickmu; James R. Young; Peter C. Thomson; Peter A. Windsor · file · #46

oon; and (iii) an 7 School of Life and Environmental Sciences, untreated control group (C). Appetite scores, lesion healing scores, and changes in The University of Sydney, Camden, NSW, dimensions of lesions…

Topical anesthesia mitigates the pain of castration in beef calves 93%
S. Lomax and P. A. Windsor · file · #50

…Windsor Faculty of Veterinary Science, University of Sydney, PMB 3, Camden, NSW 2570, Australia ABSTRACT: Castration involves the removal of the was measured as maximum pressure (g) exerted by the testes and…

Topical anaesthesia reduces sensitivity of castration wounds in neonatal piglets 48%
Sabrina Lomax; Charissa Harris; Peter A. Windsor; Peter J. White · file · #13

…White2‡* 1 Faculty of Science, School of Life and Environmental Science, The University of Sydney, Camperdown, NSW, Australia, 2 Faculty of Science, School of Veterinary Science, The University of Sydney, Camperdown, NSW…

Impact of topical anaesthesia on pain alleviation and wound healing in lambs after mulesing 46%
S LOMAX; M SHEIL; P A WINDSOR · file · #48

tudy. twice the recommended therapeutic dose (n = 12). Studies suggest that local anaesthetic infiltration can have delete- In conclusion, the topical anaesthetic and antiseptic formula- rious effects on wound healing after surgical incisions,42 but tion Tri-Solfen®, is effective at alleviating pain and enhancing impaired wound healing has generally not been apparent in wound healing in lambs post-mulesing. These results suggest clinical trials.43 We have documented a significant improvement that if widely adopted, the use of topical anaesthesia has the in wound contraction rates in lambs treated with Tri-Solfen®. In capacity to dramatically reduce the burden of acute animal Trial 1, there was an unanticipated and inadvertent discrepancy husbandry related pain and suffering in young lambs through-out in initial wound size between groups. Nevertheless improved Australia. wound healing with Tri-Solfen® was suggested by finding a sig- nificant group effect over the first 14 day evaluation period. This Acknowledgements This research program was approved by the Animal Ethics was confirmed in the second larger trial in which initial wound Committee of the University of Sydney and conforms to the size bias was eliminated. These results support the conclusions of provisions of the Declaration of Helsinki (2000). The support of Eroglu et al,44 that topical anaesthesia does not impair, and may Mr Steven Burgun and staff at Arthursleigh and Mr Geoff improve wound healing. However, it is probable that actives Moore and staff at Yerilla, the statistical support of Associate other than the local anaesthetic agents in Tri-Solfen®, such as Professor Jennifer Peat PhD and funds for handling equipment the antiseptic and the gel base may be responsible for this effect, from the

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