hyperalgesia — Quoll

Optimal pain indicators for field trial assessment of analgesic efficacy in piglets undergoing surgical castration 17%

Meredith Sheil, Adam Polkinghorne · file · #7

…Of the methods reviewed, nociceptive motor responses and/or vocal responses during the procedure, and targeted direct observation of specific pain-related behaviours, along with mechanical sensory testing for sensory hyperalgesia following…

Optimal methods of documenting analgesic efficacy in neonatal piglets undergoing castration 10%

Meredith Sheil; Adam Polkinghorne · file · #26

ost effectively evidenced by documenting a combination of reduced peripheral afferent nerve sensitisation with an associated reduction in pain-related behaviour. • Peripheral nerve sensitization (hyperalgesia) is currently most reliably and consistently documented…

Optimal Methods of Documenting Analgesic Efficacy in Neonatal Piglets Undergoing Castration 8%

Meredith Sheil and Adam Polkinghorne · file · #62

…Afferent nerve sensitisation resulting in hyperalgesia is considered the primary pathological mechanism underlying the development of post- operative inflammatory pain [10]. The threshold for eliciting the flexion reflex may be clearly measured…

Optimal methods of documenting analgesic efficacy in neonatal piglets undergoing castration 7%

Meredith Sheil; Adam Polkinghorne · file · #93

…The 35 development of hyperalgesia lowers the threshold for a response, resulting in a greater response score 36 to application of the same stimulus. This method has provided a sensitive, consistent and…

Effect of Topically Applied Anaesthetic Formulation on the Sensitivity of Scoop Dehorning Wounds in Calves 7%

Dominique McCarthy; Peter Andrew Windsor; Charissa Harris; Sabrina Lomax; Peter John White · file · #55

…Neural Mechanisms of hyperalgesia after tissue injury. Johns Hopkins APL Tech Dig. 2005; 26: 56–66. 26. Gregory NG. Pain. Physiology and behaviour of animal suffering. Oxford, UK: Blackwell Science; 2004. PLOS…

Topical anesthesia mitigates the pain of castration in beef calves 6%

S. Lomax and P. A. Windsor · file · #50

…cost of employment of a veterinarian being significant Results from both techniques of sensory testing indi- barriers to general uptake (Stafford et al., 2005; Huxley cated no significant difference in secondary hyperalgesia…

Topical anaesthesia reduces sensitivity of castration wounds in neonatal piglets 2%

Sabrina Lomax; Charissa Harris; Peter A. Windsor; Peter J. White · file · #13

…Tissue damage resulting from castration results in the localized release of chemical mediators including substance P and bradykinin, invoking an inflammatory response, with vasodilation, oedema and increased nociception leading to hyperalgesia [19…

Topical anaesthesia reduces sensitivity of castration wounds in neonatal piglets 2%

Sabrina Lomax; Charissa Harris; Peter A. Windsor; Peter J. White · file · #52

…Tissue damage resulting from castration results in the localized release of chemical mediators including substance P and bradykinin, invoking an inflammatory response, with vasodilation, oedema and increased nociception leading to hyperalgesia [19…

Topical anaesthesia reduces sensitivity of castration wounds in neonatal piglets 2%

Sabrina Lomax; Charissa Harris; Peter A. Windsor; Peter J. White · file · #80

…Tissue damage resulting from castration results in the localized release of chemical mediators including substance P and bradykinin, invoking an inflammatory response, with vasodilation, oedema and increased nociception leading to hyperalgesia [19…

Impact of topical anaesthesia on pain alleviation and wound healing in lambs after mulesing 2%

S LOMAX; M SHEIL; P A WINDSOR · file · #48

…Untreated sheep also demonstrated Pain-related behaviour increasing secondary hyperalgesia, with an increase in response Results are summarised in Figure 6 and Table 2. There was a to P stimulation of intact…