local antiseptic/anaesthetic formulation

Communication The Treatment of Contagious Ecthyma in Lambs with a Local Anaesthetic/Antiseptic Wound Formulation Lowers Serum Amyloid A Responses Aurora Ortín 1,2, * , Sergio Villanueva-Saz 1,2 , Delia Lacasta 1…

…The second formulation used an ethanol / water base as a carrier designed to evaporate follow- ing application. The most effective formulation from this trial was used in the

Posted on Authorea 16 Sep 2020 — The copyright holder is the author/funder. All rights reserved. No reuse without permission. — https://doi.org/10.22541/au.160029789.93744641 — This a preprint and has not been peer reviewed. Data may be preliminary. Efficacy and application of a novel topical anaesthetic wound formulation for treating cattle with Foot-and-Mouth disease: a field trial in Cameroon Sevidzem Lenze1 , Jacques Mavoungou1 , Kong Burinyuy1 , Koumba Armel1 , Simon Dickmu1 , James Young2 , Peter Thomson3 , and Peter Windsor2 1 Affiliation not available 2 University of Sydney 3 School of Life and Environmental Sciences September 16, 2020 Abstract Recently, a wound dressing formulation, (Tri-Solfen®, Medical Ethics Pty Ltd, Australia; TS) registered for use in ruminant husbandry in Australia, was registered for Foot-and-Mouth Disease (FMD) therapy in large ruminants in Laos, following clinical observations of improved welfare and healing following treatment of FMD lesions. In November 2019, an FMD outbreak in Cameroon provided an opportunity for a field trial, comparing clinical responses and recoveries to treatments on a sample of cattle (n = 36) comprising three equal groups of animals (n = 12), comparing responses to three treatments:(i) the application to lesions of TS, (ii) the administration of parenteral oxytetraycline commonly used for FMD in Cameroon; and (iii) an untreated control group (C). Appetite scores, lesion healing scores, and changes in dimensions of lesions, were recorded over a 15-day study period. Cattle treated with TS achieved both superior appetite and lesion healing scores with more rapid reduction in dimensions of lesions than other groups. Farmer observations indicated the TS treatment group had a more rapid return to eating with

…Alfredo Angel Benito 3 The wound dressing formulation Tri-Solfen® containing two local anaesthetics (lignocaine Maria Teresa Tejedor 4 For personal use only. and bupivacaine), adrenaline and an antiseptic (cetrimide) in a…

…The local anesthetics was likely due to the higher viscosity of the new TA and adrenalin, as combined in the experimental TA compared with the more aqueous original formulation. gel, were present…

Received: 14 March 2024 Revised: 19 May 2024 Accepted: 29 May 2024 DOI: 10.1002/vetr.4395 ORIGINAL RESEARCH Antinociceptive and wound healing effects of a commercial formulation of lidocaine, bupivacaine, adrenaline and cetrimide applied topically to superficial skin wounds in horses Shaun Pratt1 Albert Sole-Guitart1 Karla de Klerk1 Elizabeth Evans2,3 Jane Hume2,4 Chiara Palmieri1 Joanne Rainger1 Wendy Goodwin1 1 School of Veterinary Science, University of Abstract Queensland, Gatton, Queensland, Australia Background: Post-traumatic distal limb wounds cause discomfort and heal 2 Invetus, Casino, New South Wales, Australia gradually by second intention. The topical application of Tri-Solfen (lido- 3 Bioproperties, Glenorie, New South Wales, caine hydrochloride, bupivacaine hydrochloride, adrenaline acid tartrate and Australia cetrimide [LBAC]) produces effective postsurgical cutaneous analgesia in 4 Vetoquinol, Hamilton, Queensland, lambs, calves and piglets; however, its effect on wounds in horses is unknown. Australia Methods: The antinociceptive effect, measured by mechanical threshold (MT), and the wound healing impacts of LBAC compared with saline were Correspondence Shaun Pratt, School of Veterinary Science, investigated on surgically created 20 × 20 mm distal limb wounds in 10 horses. University of Queensland, Gatton, Treatment was applied once daily for 7 days following wounding on day 0. Queensland, Australia. Mechanical thresholds were measured after treatment on days 1, 2 and 3. Email: shaun.pratt@uq.edu.au Healing was observed for 25 days. Funding information Results: The topical application of LBAC immediately following wounding Invetus, Grant/Award Number: 2018002127 and its reapplication 24 hours later increased the average MT on the first post-traumatic

PRODUCTION ANIMALS Effects of a topical anaesthetic formulation and systemic carprofen, given singly or in combination, on the cortisol and behavioural responses of Merino lambs to castration DR Pauli, C Lee, iG…

…cornual nerve blocks given to all animals throughout the The TA formulation used previously and in this study, was experimental period. Repeated mechanical stimulation in modified from the original formulation designed for…

…GA), including the use of a topical wound gel formulation to provide pain relief (PR) and improve healing after surgery, containing local anaesthetics lignocaine and bupivacaine, with cetrimide and adrenalin. Forty-four…

…Topical local anaesthesia with Tri-Solfen® , (Animal Ethics Pty Ltd., Melbourne, Vic, Australia) a registered topical local anaesthetic and antiseptic formulation, applied intra- operatively by wound instillation, has recently emerged as an…