mitigation — Quoll

Optimal Methods of Documenting Analgesic Efficacy in Neonatal Piglets Undergoing Castration 85%

Meredith Sheil and Adam Polkinghorne · file · #62

…These agents act via a different mechanism and mitigate pain via blockade of neural transmission. Neural markers of pain mitigation, such as the expression of the c-fos gene and its protein…

Optimal methods of documenting analgesic efficacy in neonatal piglets undergoing castration 68%

Meredith Sheil; Adam Polkinghorne · file · #26

…These agents act via a different mechanism, and mitigate pain via blockade of neural transmission. Neural markers of pain mitigation, such as the expression of the c-fos gene and its protein…

Optimal pain indicators for field trial assessment of analgesic efficacy in piglets undergoing surgical castration 50%

Meredith Sheil, Adam Polkinghorne · file · #7

…In general (Sheil and Pain-mitigation strategies must be targeted at miti- Polkinghorne 2020), these methods look to assess piglet gating both acute and post-operative pain. This gener- pain using measurement…

Efficacy of Intra-Operative Topical Wound Anaesthesia to Mitigate Piglet Castration Pain—A Large, Multi-Centred Field Trial 5%

Meredith Sheil; Giulia Maria De Benedictis; Annalisa Scollo; Suzanne Metcalfe; Giles Innocent; Adam Polkinghorne; Flaviana Gottardo · file · #25

There is an urgent need for effective products for pain mitigation during and fol- lowing piglet castration, that are practical for use in commercial production systems. To meet regulatory requirements and achieve…

Proposed multidimensional pain outcome methodology to demonstrate analgesic drug efficacy and facilitate future drug approval for piglet castration 3%

Angela Baysinger; Sherrie R. Webb; Jennifer Brown; Johann F. Coetzee; Sara Crawford; Ashley DeDecker; Locke A. Karriker; Monique Pairis-Garcia; Mhairi A. Sutherland; Abbie V. Viscardi · file · #16

…Simply put, to measure pain mitigation, measurement of pain must be specific, quantifiable, and defined. Therefore, given the need for mitigating castration pain, a consortium of researchers, veterinarians, industry, and regulatory agencies…

Proposed multidimensional pain outcome methodology to demonstrate analgesic drug efficacy and facilitate future drug approval for piglet castration 3%

Angela Baysinger; Sherrie R. Webb; Jennifer Brown; Johann F. Coetzee; Sara Crawford; Ashley DeDecker; Locke A. Karriker; Monique Pairis-Garcia; Mhairi A. Sutherland; Abbie V. Viscardi · file · #83

…Simply put, to measure pain mitigation, measurement of pain must be specific, quantifiable, and defined. Therefore, given the need for mitigating castration pain, a consortium of researchers, veterinarians, industry, and regulatory agencies…

Topical wound anaesthesia: efficacy to mitigate piglet castration pain 2%

ML Sheil; M Chambers; B Sharpe · file · #65

…A second applied with a 30 s dwell time would be effective to mitigate pain efﬁcacy variable for pain mitigation following the procedure (postop- both during and following subsequent piglet castration. Our…

Efficacy of Intra-Operative Topical Wound Anaesthesia to Mitigate Piglet Castration Pain—A Large, Multi-Centred Field Trial 2%

Meredith Sheil; Giulia Maria De Benedictis; Annalisa Scollo; Suzanne Metcalfe; Giles Innocent; Adam Polkinghorne; Flaviana Gottardo · file · #63

There is an urgent need for effective products for pain mitigation during and fol- lowing piglet castration, that are practical for use in commercial production systems. To meet regulatory requirements and achieve…

Efficacy of Intra-Operative Topical Wound Anaesthesia to Mitigate Piglet Castration Pain—A Large, Multi-Centred Field Trial 2%

Meredith Sheil, Giulia Maria De Benedictis, Annalisa Scollo, Suzanne Metcalfe, Giles Innocent, Adam Polkinghorne, Flaviana Gottardo · file · #92

There is an urgent need for effective products for pain mitigation during and fol- lowing piglet castration, that are practical for use in commercial production systems. To meet regulatory requirements and achieve…

Optimal methods of documenting analgesic efficacy in neonatal piglets undergoing castration 2%

Meredith Sheil; Adam Polkinghorne · file · #93

…These agents act via a different mechanism, and mitigate pain via blockade of neural transmission. Neural markers of pain mitigation, such as the expression of the c-fos gene and its protein…