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Part I: understanding pain in pigs—basic knowledge about pain assessment, measures and therapy 1%
Julia Kschonek; Lara Twele; Kathrin Deters; Moana Miller; Jennifer Reinmold; Ilka Emmerich; Isabel Hennig‑Pauka; Nicole Kemper; Lothar Kreienbrock; Michael Wendt; Sabine Kästner; Elisabeth grosse Beilage · file · #100

e in the establishment of a a thermal pathway for mechanical algesia. Front Neurosci. 2021;15: nerve block by pressure or cocaine. Am J Physiol-Legacy Content. 780623. https://​doi.​org/​10.​3389/​fnins.​2021.​780623. 1929;88(4):581–91. https://​doi.​org/​10.​1152/​ajple​gacy.​1929.​88.4.​581. 30. Sandercock DA, Coe JE, Di Giminiani P, Edwards SA. Determination of 49. Self I, Grubb T. Physiology of pain. BSAVA Guide to Pain Management in stable reference genes for RT-qPCR expression data in mechanistic Small Animal Practice: BSAVA Library; 2019. p. 3–13. pain studies on pig dorsal root ganglia and spinal cord. Res Vet Sci. 50. Bosmans T, Doom M, Gasthuys F, Simoens P, Ham Lv, Polis I. Periopera‑ 2017;114:493–501. https://​doi.​org/​10.​1016/j.​rvsc.​2017.​09.​025. tive pain: physiology and pathophysiology. Vlaams Diergeneeskundig 31. Di Giminiani P, Edwards SA, Malcolm EM, Leach MC, Herskin MS, Sander‑ Tijdschrift. 2009;78(5):302–13. cock DA. Characterization of short-and long-term mechanical sensitisa‑ 51. Bishop GH, Landau WM. Evidence for a double peripheral pathway for tion following surgical tail amputation in pigs. Sci Rep. 2017;7(1):4827. pain. Science. 1958;128(3326):712–3. https://​doi.​org/​10.​1126/​scien​ce.​ https://​doi.​org/​10.​1038/​s41598-​017-​05404-y. 128.​3326.​71. 32. Di Giminiani P, Sandercock DA, Malcolm EM, Leach MC, Herskin MS, 52. Ploner M, Gross J, Timmermann L, Schnitzler A. Cortical representation Edwards SA. Application of a handheld pressure application measure‑ of first and second pain sensation in humans. Proc Natl Acad Sci USA. ment device for the characterisation of mechanical nociceptive thresh‑ 2002;99(19):12444–8.

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