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Efficacy and application of a novel topical anaesthetic wound formulation for treating cattle with Foot-and-Mouth disease: A field trial in Cameroon 1%
Sevidzem S. Lendzele; Jacques F. Mavoungou; Kong A. Burinyuy; Koumba A. Armel; Simon J. Dickmu; James R. Young; Peter C. Thomson; Peter A. Windsor · file · #46

ers (a score of 1), recoveries were observed ences in mean wound sizes amongst the three groups (all p > .25). in the two treatment groups. From Day 9 onwards, cattle treated While mean wound size increased for Control cattle, they reduced with TS had significantly higher lesion healing scores than those on for the two treatment groups, with those in the TS treatment reduc- MO (Day 9: p = .025; Day 12: p = .016; Day 15: p = .0008). None ing at a faster rate and differences were significant from Day 9, (all of the other terms had a significant association with lesion healing p < .01). There was no significant effect of Age (p = .454), Breed score: Age: p = .464; Breed: p = .311; Sex: p = .376. (p = .225), nor Sex (p = .374) on lesion size. F I G U R E 2 Model-based probabilities of obtaining lesion healing scores 1 through 4 across the six study days, for the three treatment groups 6 | LENDZELE et al. F I G U R E 3 Model-based probabilities of obtaining appetite scores 1 through 4 across the six study days, for the three treatment groups F I G U R E 4 Model-based mean lesion size (cm) across the six study days, for the three treatment groups. Shaded areas are ±1 SE of the mean LENDZELE et al. | 7 3.4 | Walking cattle having mean duration 3.72 ± 1.14 days, compared with female duration of 1.82 days. When walking is considered as an ordinal score (Immobile < With difficulty < Normal), there was a highly significant Treatment × Day interaction (p = 1.8 × 10–13). Initially (Day 0), there were no differ- 3.5 | Time on pasture ences in walking scores between the three groups (all p > .15) and some cattle remained ‘Immobile’ or ‘With difficulty’ throughout There was a highly significant Treatment × Day interaction for the the study period (Figure 5). However,

The Australian 2019/2020 Black Summer Bushfires: Analysis of the Pathology, Treatment Strategies and Decision Making About Burnt Livestock 1%
Brendan D. Cowled; Melanie Bannister-Tyrrell; Mark Doyle; Henry Clutterbuck; Jeff Cave; Alison Hillman; Karren Plain; Caitlin Pfeiffer; Michael Laurence; Michael P. Ward · file · #37

s veterinary assessment. However, for livestock that are burned could present initially as a cracked or blistered coronary band with less severity, or for well-resourced livestock owners who before complete separation between the hoof and the skin of may be able to treat stock, management options are available. the leg as the coronary band split and lost integrity. This would This section explores the several options informant veterinarians often result in the hoof falling off the foot as it would lead to considered for burnt livestock, each with relative advantages and the coronary dermis separating from the overlying hoof. The disadvantages. These include: sloughed hoof would appear normal and would leave exposed • Immediate euthanasia the underlying tissues of the hoof (e.g., underlying dermis, digital cushion and phalanx bones). These stock were extremely lame A bushfire affected livestock animal is euthanized on the farm of and were usually recumbent, or sometimes found in water bodies origin, usually with a rifle shot to the brain. (dams) which the veterinarians interpreted as an attempt to This option is indicated for stock that are severely fire affected, relieve pain. where welfare is severely compromised and that cannot be successfully treated. In general, euthanasia was reported to be Time to Develop Pathology indicated when hooves had already sloughed (or were considered Most informant veterinarians discussed that it takes several days likely to slough in the near future) or where full thickness skin for the full extent of burns to become evident. For example, burns were evident across ∼5–20% of the body or more and those on the day after a fire, burnt feet can appear relatively normal, stock were not fit to transport to an abattoir. Frontiers in

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